Early-life exposure to allergens triggers a distinct local mode of dendritic cell activation in neonatal skin without requiring migration to lymph nodes, which shapes responses to allergens in later life.
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By the end of the 21st century, only eight of the 21 cities that have hosted the Winter Olympics are projected to be cold enough to reliably host the Games due to climate change. Challenges faced by Milano Cortina 2026 organisers such as producing artificial snow, establishing transport links between remote locations and building new infrastructure are likely to become more omnipresent at future editions.
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