更为关键的是，此前全球范围内并无经Ⅲ期临床试验确证疗效的CIN2非手术治疗产品，患者要么面临长期随访的癌变风险，要么被迫接受创伤性手术，难以实现“早干预、少损伤”的防控要求。APL-1702的出现，让CIN2真正成为宫颈癌防控的“黄金节点”，将推动临床诊疗重心向CIN2阶段前移，助力宫颈癌防治体系实现跨越式升级。
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Cluster & Border Point Definition: The map is divided into clusters, and border points are identified using the Ford-Fulkerson based method.
Head teacher Michael Polly, played by David Morissey, is the prime suspect in his wife's disappearance，这一点在体育直播中也有详细论述